Malaysia’s health ministry found a virus that is ten times infectious than the coronavirus (COVID 19) known as D614G.
D614G is a mutation of the SARS-CoV-2 virus, which causes Covid19. D614G mutation, first found in February in Europe and since then it has become the supreme variant of SARS-CoV-2 virus cluster
Researchers has found that the virus has undergone different mutation since December-19.
This dangerous mutated virus appeared after the Wuhan outbreak, most probably in Italy. As per BBC report in July, This strain is noticed in almost 97% of the samples worldwide.
A computational biologist & population geneticist, Dr. Bette Korber, quoted that “D614G appears to be dominant everywhere including china. This one is quite better at spreading between people that the original one, whenever there is collision of both the version new one will took over the another.”
In a study conducted by New York Genome Centre at New York University, Researchers found that the newly mutated virus is more transmissible than the old one. However, it’s still unclear how representative the lab results are of transmission in real patients.
Study published in CELL, by Dr.Korber& by WHO collaborating center in china too, gave similar results that D614G is ten times more infectious than the original virus from Wuhan.
Initially, it was theorized that we need to develop separate vaccines for different mutated variants. However, most of vaccines in development are based on a different region of the spike of a virus, so this should not impact their development.
D614G mutation happened in the viral spike protein, it does not change the receptor-binding domain (RBD) at the tip of the spike protein. The RBD binds to the ACE2 receptor on human cells; It is also the main target of the Immune System.
It alters the spike protein but not the critical RBD immunogenic part.
According to the researchers, most circulating SARS-CoV-2 is D614D variant; One vaccine is likely to handle the situation.